| 1 | Star Wars: The Force Awakens | 2015-12-15 | $245M | $992.64M | 4.05 |
| 2 | Avengers: Endgame | 2019-04-24 | $356M | $918.37M | 2.58 |
| 3 | Black Panther | 2018-02-13 | $200M | $725.26M | 3.63 |
| 4 | Avengers: Infinity War | 2018-04-25 | $300M | $717.82M | 2.39 |
| 5 | Jurassic World | 2015-06-06 | $150M | $670.7M | 4.47 |
| 6 | Star Wars: The Last Jedi | 2017-12-13 | $200M | $665.18M | 3.33 |
| 7 | The Lion King | 2019-07-12 | $260M | $566.64M | 2.18 |
| 8 | Rogue One: A Star Wars Story | 2016-12-14 | $200M | $562.54M | 2.81 |
| 9 | Beauty and the Beast | 2017-03-16 | $160M | $520.31M | 3.25 |
| 10 | Avengers: Age of Ultron | 2015-04-22 | $365M | $483.6M | 1.32 |
| 11 | Guardians of the Galaxy Vol. 2 | 2017-04-19 | $200M | $406.81M | 2.03 |
| 12 | Deadpool | 2016-02-09 | $58M | $375.74M | 6.48 |
| 13 | The Jungle Book | 2016-04-07 | $175M | $368.2M | 2.10 |
| 14 | Aladdin | 2019-05-22 | $183M | $362.56M | 1.98 |
| 15 | Batman v Superman: Dawn of Justice | 2016-03-23 | $250M | $358.06M | 1.43 |
| 16 | Deadpool 2 | 2018-05-10 | $110M | $343.06M | 3.12 |
| 17 | Thor: Ragnarok | 2017-10-02 | $180M | $329.56M | 1.83 |
| 18 | Doctor Strange | 2016-10-25 | $180M | $242.04M | 1.34 |
| 19 | Justice League | 2017-11-15 | $300M | $242.02M | 0.81 |
| 20 | Ant-Man and the Wasp | 2018-07-04 | $140M | $228.15M | 1.63 |
| 21 | Solo: A Star Wars Story | 2018-05-15 | $250M | $227.87M | 0.91 |
| 22 | Venom | 2018-09-28 | $116M | $223.51M | 1.93 |
| 23 | A Quiet Place | 2018-04-03 | $17M | $192.32M | 11.31 |
| 24 | Ant-Man | 2015-07-14 | $130M | $184.75M | 1.42 |
| 25 | Kong: Skull Island | 2017-03-08 | $185M | $171.75M | 0.93 |
| 26 | A Quiet Place Part II | 2021-05-21 | $61M | $165.02M | 2.71 |
| 27 | War for the Planet of the Apes | 2017-07-11 | $150M | $151.84M | 1.01 |
| 28 | Pokémon Detective Pikachu | 2019-05-03 | $150M | $149.81M | 1.00 |
| 29 | Sonic the Hedgehog | 2020-02-12 | $85M | $149.07M | 1.75 |
| 30 | Ready Player One | 2018-03-28 | $175M | $137.02M | 0.78 |
| 31 | The Legend of Tarzan | 2016-06-29 | $180M | $129.19M | 0.72 |
| 32 | A Wrinkle in Time | 2018-03-08 | $103M | $100.48M | 0.98 |
| 33 | Rampage | 2018-04-11 | $120M | $99.35M | 0.83 |
| 34 | Terminator Genisys | 2015-06-23 | $155M | $92.06M | 0.59 |
| 35 | Miss Peregrine's Home for Peculiar Children | 2016-09-27 | $110M | $88.43M | 0.80 |
| 36 | Alita: Battle Angel | 2019-01-31 | $170M | $88.24M | 0.52 |
| 37 | Teenage Mutant Ninja Turtles: Out of the Shadows | 2016-06-01 | $135M | $84.05M | 0.62 |
| 38 | Ted 2 | 2015-06-25 | $68M | $83.88M | 1.23 |
| 39 | Alice Through the Looking Glass | 2016-05-25 | $170M | $78.54M | 0.46 |
| 40 | Paddington | 2014-11-24 | $55M | $76.4M | 1.39 |
| 41 | The Hobbit: The Battle of the Five Armies | 2014-12-10 | $250M | $65.57M | 0.26 |
| 42 | Into the Woods | 2014-12-24 | $50M | $62.67M | 1.25 |
| 43 | Fantastic Four | 2015-08-05 | $120M | $58.75M | 0.49 |
| 44 | The BFG | 2016-06-01 | $140M | $56.26M | 0.40 |
| 45 | The Nutcracker and the Four Realms | 2018-10-26 | $120M | $55.48M | 0.46 |
| 46 | Warcraft | 2016-05-25 | $160M | $50.33M | 0.31 |
| 47 | The Huntsman: Winter's War | 2016-04-06 | $115M | $49M | 0.43 |
| 48 | Valerian and the City of a Thousand Planets | 2017-07-20 | $177M | $42.18M | 0.24 |
| 49 | Paddington 2 | 2017-11-09 | $40M | $40.77M | 1.02 |
| 50 | Pan | 2015-09-24 | $150M | $35.74M | 0.24 |